Physics Nobel awarded for optogenetics — light-controlled neurons
The Nobel Prize in Physics was awarded to Karl Deisseroth, Peter Hegemann, and Georg Nagel for the development of optogenetics — the technique that uses light-sensitive proteins from algae to switch individual neurons on and off in living tissue, transforming mechanistic neuroscience.
- Hegemann and Nagel characterised channelrhodopsins from algae; Deisseroth deployed them in neurons
- Enabled the first real-time circuit-level mapping of how brain regions communicate during behaviour
- Nobel explicitly recognises the physical mechanism of ion channel gating by light — biophysics at its core